SAPNA - Volume-2 , Issue-4, January 2025

Pages: 124-127

EVALUATION OF INVITRO ANTI-DIABETIC ACTIVITY OF AREVA LANATA WHOLE PLANT EXTRACT

Swathi Krishna K Venkataa, *, Chandrasekhar Kothapalli Bonnothb, Nazma Sultana Mohameda, MohasinMohamed

Category: Subjects

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Abstract:

Objective: The aim of the present study is to evaluate the in vitro anti-diabetic activity of Areva lanata whole plant extract by inhibiting α-amylase and α-glucosidase enzymes.

Methods: Different solvent extracts of Areva lanata were prepared in which the aqueous extract showed high enzyme inhibition when compared to other solvents. In order to prevent oxidative stress-induced diabetes, Areva lanata whole plant extract is used which inhibits alpha-amylase and alpha-glucosidase enzymes in a dose dependent manner.

Results: The phytochemical screening for successive solvent extraction of Areva lanata confirmed the presence several bioactive compounds like alkaloids, flavonoids (quercetin), tannins, carotenoids, lycopene, carbohydrates, terpenoids, saponins, cardiac glycosides and phenols. And it showed a significant anti-hyperglycemic activity.

Conclusion: whole plant extract of Areva lanata contains dose dependent antihyperglycemic activity.

Keywords: Diabetes, Areva lanata, Anti-hyperglycemic activity, solvent extraction.